Alcohol potentiates the sedating effects of certain

Patients taking trazadone are advised to avoid alcohol.

It is also important to inform your doctor about all the prescription and over-the-counter drugs that you are taking.

Morphine, Codeine, Oxycodone etc.) for prolonged periods is NOT recommended.

Some substances which are a GABA RECEPTOR AGONIST also have a number of other useful physiological beneficial effects that you might wish to benefit from (e.g.

Equivocal efficacy for management of eating disorders† (e.g., bulimia†, anorexia nervosa†); avoid use in underweight individuals and in those exhibiting suicidal ideation.

Alternatively, in patients who do not tolerate larger dosages, initial dosage of amitriptyline hydrochloride 37.5 or 50 mg daily (in fixed combination with chlordiazepoxide 15 or 20 mg daily, respectively) in divided doses. Practice guideline for the treatment of patients with major depressive disorder (revision).

(See Boxed Warning and also see Pediatric Use under Cautions.) Anxiety, agitation, panic attacks, insomnia, irritability, hostility, aggressiveness, impulsivity, akathisia, hypomania, and/or mania may be precursors to emerging suicidality.

Consider changing or discontinuing therapy in patients whose depression is persistently worse or in those with emerging suicidality or symptoms that might be precursors to worsening depression or suicidality, particularly if severe, abrupt in onset, or not part of patient’s presenting symptoms.

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Appropriately monitor and closely observe patients receiving amitriptyline for any reason, particularly during initiation of therapy (i.e., the first few months) and during periods of dosage adjustments. Elavil (amitriptyline hydrochloride tablets and injection) prescribing information. Please kindly note that I am NOT stating that GABA RECEPTOR AGONISTS have no valuable medicinal use, nor am I suggesting that they should NEVER be taken in any circumstance.

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